:root{
  --paper:#F7F5F0; --paper2:#FDFCFA; --card:#FFFFFF;
  --ink:#1A1E1C; --ink-soft:#565C57; --ink-faint:#8A9089;
  --accent:#1F4D3F; --accent-soft:#E7EDE9; --accent-line:#C7D6CE;
  --copper:#A9662E; --copper-soft:#F3ECE3; --copper-line:#E7D6C4;
  --line:#E3DED3; --line-strong:#D3CCBD;
  --good:#1F6E4F; --warn:#B0743C; --bad:#9C4A38;
  --serif:"Iowan Old Style","Palatino Linotype",Palatino,"Book Antiqua",Georgia,serif;
  --sans:-apple-system,BlinkMacSystemFont,"Segoe UI",system-ui,Helvetica,Arial,sans-serif;
  --mono:"SF Mono",ui-monospace,"JetBrains Mono",Menlo,Consolas,monospace;
}
*{box-sizing:border-box}
html{scroll-behavior:smooth}
body{margin:0;background:var(--paper);color:var(--ink);font-family:var(--sans);
  font-size:16px;line-height:1.6;-webkit-font-smoothing:antialiased;letter-spacing:-0.003em}
svg{display:block}
img{display:block}
a{color:inherit;text-decoration:none}
button{font-family:inherit}
.wrap{max-width:1240px;margin:0 auto;padding:0 32px}
.eyebrow{text-transform:uppercase;letter-spacing:.16em;font-size:.72rem;font-weight:600;color:var(--accent)}
h1,h2,h3{font-family:var(--serif);font-weight:600;letter-spacing:-0.01em;text-wrap:balance;margin:0}
.mono{font-family:var(--mono)}
.hidden{display:none!important}

/* ---------------- nav ---------------- */
.nav{position:sticky;top:0;z-index:60;background:rgba(247,245,240,.85);
  backdrop-filter:saturate(140%) blur(10px);border-bottom:1px solid var(--line)}
.nav .wrap{display:flex;align-items:center;gap:26px;height:64px}
.brand{font-family:var(--serif);font-size:1.32rem;font-weight:600;display:flex;align-items:center;gap:9px;cursor:pointer}
.brand .dot{width:9px;height:9px;border-radius:2px;background:var(--accent);transform:rotate(45deg)}
.chip{font-family:var(--mono);font-size:.6rem;letter-spacing:.06em;text-transform:uppercase;
  color:var(--accent);border:1px solid var(--accent-line);border-radius:999px;padding:2px 8px}
.nav .links{display:flex;gap:6px;margin-left:auto}
.nav .links a{padding:7px 13px;border-radius:8px;font-size:.92rem;color:var(--ink-soft);transition:.14s}
.nav .links a:hover{color:var(--ink);background:#fff}
.nav .links a.active{color:var(--accent);background:var(--accent-soft);font-weight:600}
.btn{font-size:.9rem;font-weight:600;border-radius:8px;padding:9px 15px;cursor:pointer;
  display:inline-flex;align-items:center;gap:7px;transition:.16s;border:1px solid transparent}
.btn-primary{background:var(--accent);color:#fff}
.btn-primary:hover{background:#173a30}
.btn-ghost{background:transparent;color:var(--ink);border-color:var(--line-strong)}
.btn-ghost:hover{border-color:var(--ink);background:#fff}
.btn-sm{padding:6px 11px;font-size:.82rem}

/* ---------------- landing ---------------- */
.hero{position:relative;overflow:hidden;border-bottom:1px solid var(--line)}
.hero-bg{position:absolute;inset:0;pointer-events:none;z-index:0}
.hero-bg .tile{position:absolute;width:150px;opacity:.06}
.hero-bg .tile img{width:100%}
.hero-veil{position:absolute;inset:0;z-index:1;pointer-events:none;
  background:radial-gradient(120% 90% at 30% 20%,rgba(247,245,240,.35) 0%,rgba(247,245,240,.72) 45%,var(--paper) 88%)}
.hero .wrap{position:relative;z-index:2;display:grid;grid-template-columns:1.15fr .85fr;gap:56px;
  align-items:center;padding-top:72px;padding-bottom:80px}
.hero-copy{animation:rise .7s cubic-bezier(.2,.7,.2,1) both}
.hero h1{font-size:clamp(2.3rem,4.6vw,4rem);line-height:1.04;margin:16px 0 0}
.hero h1 .u{color:var(--accent);font-style:italic}
.hero .lede{font-size:1.14rem;color:var(--ink-soft);max-width:35ch;margin:22px 0 30px;line-height:1.55}
.hero .cta{display:flex;gap:13px;flex-wrap:wrap}
.hero .meta{margin-top:26px;font-family:var(--mono);font-size:.76rem;color:var(--ink-faint)}
.route-card-hero{background:var(--card);border:1px solid var(--line);border-radius:14px;padding:20px 20px 16px;
  box-shadow:0 1px 2px rgba(26,30,28,.04),0 22px 46px -26px rgba(26,30,28,.28);
  animation:rise .7s .12s cubic-bezier(.2,.7,.2,1) both;cursor:pointer}
.route-card-hero .rc-head{display:flex;justify-content:space-between;font-family:var(--mono);
  font-size:.66rem;letter-spacing:.04em;color:var(--ink-faint);text-transform:uppercase}
.route-card-hero .ok{color:var(--accent);font-weight:600}
.route-card-hero .struct{background:linear-gradient(180deg,#fff,#fbfaf7);border:1px solid var(--line);
  border-radius:9px;margin:12px 0;padding:10px}
.route-card-hero .struct img{width:100%;max-height:230px;object-fit:contain}
.stats-band{background:var(--paper2);border-bottom:1px solid var(--line)}
.stats-band .wrap{display:grid;grid-template-columns:repeat(5,1fr);gap:20px;padding:36px 32px}
.stat .n{font-family:var(--serif);font-size:2.4rem;font-weight:600;font-variant-numeric:tabular-nums;line-height:1}
.stat .n .s{color:var(--accent)}
.stat .l{font-size:.76rem;text-transform:uppercase;letter-spacing:.1em;color:var(--ink-soft);margin-top:8px}
.stat+.stat{border-left:1px solid var(--line);padding-left:22px}
.home-section{padding:70px 0;border-bottom:1px solid var(--line)}
.home-section .head{max-width:640px;margin-bottom:36px}
.home-section h2{font-size:clamp(1.7rem,2.8vw,2.4rem);margin-top:10px}
.home-section .sub{color:var(--ink-soft);font-size:1.03rem;margin-top:12px}
.explore-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:18px}
.explore-card{background:var(--card);border:1px solid var(--line);border-radius:12px;padding:22px;cursor:pointer;transition:.16s}
.explore-card:hover{border-color:var(--accent-line);transform:translateY(-2px);box-shadow:0 16px 36px -28px rgba(26,30,28,.4)}
.explore-card .ec-n{font-family:var(--serif);font-size:1.9rem;color:var(--accent);font-variant-numeric:tabular-nums}
.explore-card h3{font-size:1.1rem;margin:8px 0 6px}
.explore-card p{color:var(--ink-soft);font-size:.9rem;margin:0}

/* ---------------- page header + toolbar ---------------- */
.page{padding:40px 0 90px;min-height:70vh}
.page-head{display:flex;justify-content:space-between;align-items:flex-end;gap:20px;margin-bottom:24px;flex-wrap:wrap}
.page-head h1{font-size:2rem}
.page-head .count{color:var(--ink-faint);font-family:var(--mono);font-size:.82rem;margin-top:4px}
.toolbar{display:flex;gap:10px;flex-wrap:wrap;align-items:center;margin-bottom:26px;
  padding:14px 16px;background:var(--paper2);border:1px solid var(--line);border-radius:12px}
.toolbar input[type=search],.toolbar select{font-family:inherit;font-size:.88rem;color:var(--ink);
  background:#fff;border:1px solid var(--line-strong);border-radius:8px;padding:8px 11px}
.toolbar input[type=search]{min-width:230px;flex:1}
.toolbar label{font-size:.78rem;color:var(--ink-soft);display:inline-flex;align-items:center;gap:6px}
.toolbar .seg{display:flex;border:1px solid var(--line-strong);border-radius:8px;overflow:hidden}
.toolbar .seg button{background:#fff;border:none;padding:7px 12px;font-size:.82rem;color:var(--ink-soft);cursor:pointer}
.toolbar .seg button.on{background:var(--accent);color:#fff}
.tags{display:flex;gap:6px;flex-wrap:wrap}
.tag{font-size:.76rem;padding:5px 11px;border-radius:999px;border:1px solid var(--line-strong);
  background:#fff;color:var(--ink-soft);cursor:pointer;transition:.14s}
.tag.on{background:var(--accent);color:#fff;border-color:var(--accent)}
.reliable-toggle{font-weight:600;color:var(--accent);background:var(--accent-soft);
  border:1px solid var(--accent-line);border-radius:8px;padding:8px 12px;display:inline-flex;align-items:center;gap:7px}
.reliable-toggle .hint2{font-weight:400;color:var(--ink-faint);font-size:.74rem}
.count a{color:var(--accent);text-decoration:none;border-bottom:1px solid var(--accent-line)}
.count a:hover{border-color:var(--accent)}

/* ---------------- badges ---------------- */
.badge{font-size:.72rem;font-weight:600;padding:3px 9px;border-radius:999px;
  background:var(--accent-soft);color:var(--accent);border:1px solid var(--accent-line);white-space:nowrap}
.badge.alt{background:var(--copper-soft);color:var(--copper);border-color:var(--copper-line)}
.badge.gray{background:#EFEDE6;color:var(--ink-soft);border-color:var(--line-strong)}
.badge.key{background:#F6EEDD;color:#8A6320;border-color:#E7D6A8}
.feas{font-weight:700;text-transform:capitalize}
.feas-excellent{color:var(--good)} .feas-good{color:var(--good)}
.feas-moderate{color:var(--warn)} .feas-fair{color:var(--warn)}
.feas-acceptable{color:var(--warn)} .feas-fair2{color:var(--warn)}
.feas-poor{color:var(--bad)} .feas-challenging{color:var(--bad)} .feas-infeasible{color:var(--bad)}

/* ---------------- gallery cards ---------------- */
.grid{display:grid;gap:18px}
.grid.routes{grid-template-columns:repeat(auto-fill,minmax(270px,1fr))}
.grid.mols{grid-template-columns:repeat(auto-fill,minmax(190px,1fr))}
.grid.rxns{grid-template-columns:repeat(auto-fill,minmax(360px,1fr))}
.card{background:var(--card);border:1px solid var(--line);border-radius:13px;overflow:hidden;
  cursor:pointer;transition:.16s;display:flex;flex-direction:column}
.card:hover{border-color:var(--accent-line);transform:translateY(-2px);box-shadow:0 18px 40px -30px rgba(26,30,28,.45)}
.card .thumb{background:linear-gradient(180deg,#fff,#fbfaf7);border-bottom:1px solid var(--line);
  padding:12px;display:flex;align-items:center;justify-content:center;height:190px}
.card .thumb img{max-width:100%;max-height:166px;object-fit:contain}
.card .body{padding:14px 15px 15px}
.card .cid{font-family:var(--mono);font-size:.74rem;color:var(--ink-faint)}
.card .ctitle{font-family:var(--serif);font-size:1.02rem;margin:3px 0 4px;line-height:1.25}
.card .org{font-style:italic;font-size:.78rem;color:var(--ink-faint);margin:0 0 10px}
.org-inline{font-style:italic}
.card .meta-badges{display:flex;flex-wrap:wrap;gap:6px}
.scorebar{display:flex;gap:6px;margin:2px 0 10px}
.sc{flex:1;text-align:center;border-radius:7px;padding:4px 2px;font-family:var(--serif);font-weight:600;
  font-size:1rem;font-variant-numeric:tabular-nums;line-height:1.05}
.sc i{display:block;font-family:var(--sans);font-style:normal;font-weight:600;font-size:.55rem;
  text-transform:uppercase;letter-spacing:.06em;opacity:.72;margin-top:1px}
.sc-o{background:var(--accent-soft);color:var(--accent);border:1px solid var(--accent-line)}
.sc-g{background:#E7F0E4;color:#2E6B33;border:1px solid #CADEC4}
.sc-f{background:var(--copper-soft);color:var(--copper);border:1px solid var(--copper-line)}
.scorebar.big .sc{padding:10px 4px;font-size:1.7rem}
.scorebar.big .sc i{font-size:.62rem;margin-top:3px}
.mol-card .thumb{height:150px}.mol-card .thumb img{max-height:128px}
.mol-card .formula{font-family:var(--mono);font-size:.8rem;color:var(--ink)}
.mol-card .sub{font-size:.72rem;color:var(--ink-faint);margin-top:3px}
.target-dot{display:inline-block;width:7px;height:7px;border-radius:50%;background:var(--accent);margin-right:5px;vertical-align:middle}

/* ---------------- reaction scheme ---------------- */
.scheme{display:flex;align-items:center;gap:12px;flex-wrap:wrap;justify-content:center}
.scheme .mol{width:130px}.scheme .mol img{width:100%}
.scheme .mol.big{width:180px}
.scheme .plus{font-family:var(--serif);font-size:1.3rem;color:var(--ink-faint)}
/* compact scheme used in reaction cards */
.scheme.mini{gap:6px;flex-wrap:nowrap;align-items:center}
.scheme.mini .mol{width:84px;flex:0 0 auto}
.scheme.mini .mol.big{width:104px}
.scheme.mini .plus{font-size:1rem}
.scheme.mini .arrow-wrap{min-width:54px;flex:0 1 64px}
.scheme.mini .arrow-wrap .arrow{min-width:44px}
.rxn-card{cursor:default}
.rxn-card .rxn-top{display:flex;align-items:center;justify-content:center;padding:16px;min-height:158px;
  border-bottom:1px solid var(--line);background:linear-gradient(180deg,#fff,#fbfaf7);cursor:pointer;overflow:hidden}
.rxn-card .rxn-cond{font-family:var(--mono);font-size:.72rem;color:var(--ink-soft);
  padding:11px 15px 0;line-height:1.35}
.arrow-wrap{display:flex;flex-direction:column;align-items:center;min-width:150px;flex:1}
.arrow-wrap .cond{font-family:var(--mono);font-size:.66rem;color:var(--ink-soft);text-align:center;
  margin-bottom:5px;max-width:230px;line-height:1.3}
.arrow-wrap .arrow{height:2px;width:100%;min-width:110px;background:var(--copper);position:relative}
.arrow-wrap .arrow:after{content:"";position:absolute;right:-1px;top:-4px;border-left:9px solid var(--copper);
  border-top:5px solid transparent;border-bottom:5px solid transparent}
.arrow-wrap .rxn-class{font-size:.68rem;color:var(--copper);font-weight:600;margin-top:6px;text-align:center}

/* ---------------- route detail ---------------- */
.detail{display:grid;grid-template-columns:1fr 340px;gap:44px;align-items:start}
.back{font-size:.85rem;color:var(--ink-soft);margin-bottom:18px;display:inline-block}
.back:hover{color:var(--accent)}
.route-switch{display:flex;align-items:center;gap:8px;flex-wrap:wrap;margin:4px 0 26px;
  padding:13px 15px;background:var(--accent-soft);border:1px solid var(--accent-line);border-radius:12px}
.route-switch .rs-label{font-size:.82rem;color:var(--accent);font-weight:600;margin-right:2px}
.rs-chip{font-size:.8rem;padding:6px 12px;border-radius:999px;background:#fff;
  border:1px solid var(--accent-line);color:var(--ink-soft);transition:.14s;white-space:nowrap}
.rs-chip:hover{border-color:var(--accent);color:var(--ink)}
.rs-chip.on{background:var(--accent);color:#fff;border-color:var(--accent)}
.rs-chip.on .feas,.rs-chip.on b{color:#fff}
.rs-more{display:inline-flex;gap:8px;align-items:center}
.rs-more-btn{font-family:var(--sans);font-size:.8rem;padding:6px 12px;border-radius:999px;cursor:pointer;
  background:transparent;border:1px dashed var(--line-strong);color:var(--ink-soft);white-space:nowrap}
.rs-more-btn:hover{border-color:var(--accent);color:var(--ink)}
.rs-more-list{display:none;gap:8px}
.rs-more.open .rs-more-list{display:inline-flex;flex-wrap:wrap}
.rs-more.open .rs-more-btn{display:none}
.route-summary{font-family:var(--serif);font-size:1.18rem;line-height:1.5;
  border-left:3px solid var(--accent);padding-left:20px;margin:20px 0 34px}
.step-note.route-critic{margin:-14px 0 22px;font-size:.98rem}
.constraint-note{background:var(--copper-soft);border:1px solid var(--copper-line);border-radius:10px;
  padding:12px 16px;margin:0 0 22px;font-size:.88rem;color:var(--ink)}
.constraint-note .lbl{display:block;font-size:.66rem;text-transform:uppercase;letter-spacing:.1em;
  color:var(--copper);font-weight:700;margin-bottom:4px}
/* full-route overview (JACS-style strip) */
.overview{position:relative;background:var(--card);border:1px solid var(--line);border-radius:14px;padding:20px 22px;margin:0 0 28px}
.fig-expand{position:absolute;bottom:14px;right:14px;z-index:4;background:#fff;
  border:1px solid var(--line-strong);border-radius:8px;width:32px;height:32px;
  font-size:1rem;line-height:1;cursor:pointer;color:var(--ink-soft)}
.fig-expand:hover{color:var(--ink);border-color:var(--ink)}
.fig-modal{position:fixed;inset:0;z-index:100;background:rgba(20,24,22,.72);
  display:flex;align-items:center;justify-content:center;padding:28px}
.fig-modal-body{background:#fff;border-radius:14px;padding:26px;max-width:96vw;max-height:92vh;overflow:auto}
.fig-modal .fig-expand{display:none}
.fig-modal .scheme .mol{width:220px}
.fig-modal .scheme .mol.big{width:300px}
.fig-modal .scheme{gap:22px}
.fig-modal .step-scheme{border:none;padding:0;margin:0}
.fig-close{position:fixed;top:22px;right:26px;z-index:101;background:#fff;border:1px solid var(--line-strong);
  border-radius:50%;width:36px;height:36px;cursor:pointer;font-size:1rem}
.ov-head{display:flex;justify-content:space-between;align-items:baseline;margin-bottom:14px;gap:12px;flex-wrap:wrap}
.ov-hint{font-size:.78rem;color:var(--ink-faint)}
.overview-inner{display:flex;flex-wrap:wrap;align-items:center;gap:4px}
.ov-unit{display:flex;align-items:center;flex:0 0 auto}
.ov-node{width:96px;flex:0 0 auto;cursor:pointer;border:1px solid transparent;border-radius:9px;
  padding:6px 6px 4px;transition:.14s;background:#fff}
.ov-node img{width:100%;height:auto}
.ov-node:hover{border-color:var(--accent);background:var(--accent-soft);transform:translateY(-2px)}
.ov-node.key{background:linear-gradient(180deg,#fff,var(--copper-soft))}
.ov-node.target{background:linear-gradient(180deg,#fff,var(--accent-soft))}
.ov-tag{display:block;text-align:center;font-family:var(--mono);font-size:.6rem;color:var(--ink-faint);
  margin-top:2px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}
.ov-node.key .ov-tag{color:var(--copper)}
.ov-node.target .ov-tag{color:var(--accent);font-weight:600}
.ov-tag.start{color:var(--ink-soft)}
.ov-tag.keyint{color:var(--copper);font-weight:700;white-space:normal;overflow:visible;line-height:1.2}
.ov-arrow{flex:0 0 auto;min-width:66px;display:flex;flex-direction:column;justify-content:center;align-items:center;cursor:pointer}
.ov-arrow .line{width:40px;height:2px;background:var(--copper);position:relative}
.ov-arrow .line:after{content:"";position:absolute;right:-1px;top:-3px;
  border-left:7px solid var(--copper);border-top:4px solid transparent;border-bottom:4px solid transparent}
.ov-arrow .ov-step{font-family:var(--mono);font-size:.6rem;color:var(--ink-faint);margin-top:5px;white-space:nowrap}
.ov-arrow:hover .ov-step{color:var(--ink)}
.ov-arrow.key .line{background:var(--copper);height:2.5px}
.ov-arrow.key .line:after{border-left-color:var(--copper)}
.ov-arrow.key .ov-step{color:var(--copper);font-weight:700}
.ov-node.rx-key{background:linear-gradient(180deg,#fff,var(--copper-soft));
  border-color:var(--copper-line);box-shadow:0 10px 22px -12px rgba(169,102,46,.4)}
/* convergent/mixed tree — Cytoscape + dagre graph, real per-molecule node sizes */
.cy-tree{width:100%;height:320px;border:1px solid var(--line);border-radius:10px;background:#fff;cursor:default}
.tree-detailed-wrap{padding:4px 2px 2px}
.cy-tree.detailed{width:min(94vw,1700px);height:min(86vh,1000px);border:none;cursor:grab}
.cy-tree.detailed:active{cursor:grabbing}

.step{background:var(--card);border:1px solid var(--line);border-radius:14px;padding:22px;margin-bottom:18px;scroll-margin-top:80px}
.step.key{border-color:var(--copper-line);box-shadow:0 0 0 3px var(--copper-soft)}
.step.flash{box-shadow:0 0 0 3px var(--accent);transition:box-shadow .2s}
.step-head{display:flex;align-items:center;gap:10px;margin-bottom:14px}
.step-num{width:26px;height:26px;border-radius:7px;background:var(--accent);color:#fff;font-size:.8rem;
  font-weight:700;display:flex;align-items:center;justify-content:center;flex-shrink:0}
.step-class{font-weight:600;font-size:.98rem}
.step-scheme{position:relative;border-top:1px solid var(--line);border-bottom:1px solid var(--line);padding:36px 0 18px;margin:14px 0}
.num-toggle{position:absolute;top:8px;right:0;font-size:.72rem;color:var(--ink-faint);
  display:inline-flex;align-items:center;gap:5px;cursor:pointer;user-select:none}
.num-toggle:hover{color:var(--ink)}
.step-note{font-size:.92rem;color:var(--ink-soft);margin:10px 0 0}
.step-note .lbl{font-size:.68rem;text-transform:uppercase;letter-spacing:.1em;color:var(--ink-faint);font-weight:600;margin-bottom:3px}
.step-note .mono{font-family:var(--mono);font-size:.86rem}
.risk-note{color:var(--copper)}
.verdict{display:inline-flex;align-items:center;gap:8px;font-weight:600;font-size:.84rem;color:var(--accent);
  background:var(--accent-soft);border:1px solid var(--accent-line);border-radius:8px;padding:7px 12px;margin-top:12px}
.verdict .tick{width:16px;height:16px;border-radius:50%;background:var(--accent);color:#fff;
  display:inline-flex;align-items:center;justify-content:center;font-size:.66rem}
.verdict.bad{color:var(--bad);background:#F6E9E5;border-color:#E4C6BD}
.verdict.bad .tick{background:var(--bad)}
.cond-chip{font-family:var(--mono);font-size:.82rem;background:var(--paper);border:1px solid var(--line);
  border-radius:7px;padding:8px 11px;color:var(--ink);display:inline-block}
.step-details{margin-top:12px;border-top:1px dashed var(--line);padding-top:10px}
.step-details summary{cursor:pointer;font-size:.68rem;text-transform:uppercase;letter-spacing:.1em;color:var(--ink-faint);font-weight:600}
.step-details p{margin:9px 0 0;color:var(--ink-soft);font-size:.92rem}
.reason-details summary{cursor:pointer;color:var(--ink-soft);font-size:.92rem;list-style:none}
.reason-details summary::-webkit-details-marker{display:none}
.reason-details summary::after{content:" ▸ read more";color:var(--accent);font-weight:600;font-size:.8rem;white-space:nowrap}
.reason-details[open] summary::after{content:""}
.reason-details p{margin:9px 0 0;color:var(--ink-soft);font-size:.92rem}
.aside-p{font-size:.86rem;color:var(--ink-soft);margin:0;line-height:1.5}
.risk-list em{color:var(--accent);font-style:normal;display:block;margin-top:3px}
.step-jump{color:var(--accent);cursor:pointer;font-weight:600;white-space:nowrap}
.step-jump:hover{text-decoration:underline}
.aside-card{background:var(--card);border:1px solid var(--line);border-radius:14px;padding:20px;margin-bottom:16px}
.aside-card h3{font-size:.78rem;text-transform:uppercase;letter-spacing:.11em;color:var(--ink-faint);font-weight:600;margin-bottom:14px}
.spec-row{display:flex;justify-content:space-between;padding:9px 0;border-bottom:1px solid var(--line);font-size:.9rem}
.spec-row:last-child{border-bottom:none}
.spec-row .v{font-weight:600;font-variant-numeric:tabular-nums}
.risk-list{list-style:none;padding:0;margin:0}
.risk-list li{font-size:.85rem;color:var(--ink-soft);padding:8px 0;border-bottom:1px solid var(--line)}
.risk-list li:last-child{border-bottom:none}
.risk-list b{color:var(--ink);display:block;margin-bottom:2px}
/* molecule-index key */
.molkey{display:grid;grid-template-columns:repeat(3,1fr);gap:8px}
.mk{border:1px solid var(--line);border-radius:9px;padding:6px 6px 4px;cursor:pointer;
  background:linear-gradient(180deg,#fff,#fbfaf7);transition:.14s;text-align:center}
.mk:hover{border-color:var(--accent-line);transform:translateY(-1px)}
.mk-img img{width:100%;height:auto;max-height:66px;object-fit:contain}
.mk-lbl{font-family:var(--serif);font-weight:600;font-size:.9rem;color:var(--accent)}
.mk-hint{font-size:.72rem;color:var(--ink-faint);margin-top:9px;line-height:1.35}
.risk-list li.bb{display:flex;gap:10px;align-items:center}
.bb .bb-img{flex:0 0 46px;width:46px;border:1px solid var(--line);border-radius:7px;padding:2px;cursor:pointer;background:#fff}
.bb .bb-img img{width:100%;height:auto}
.bb .bb-txt{flex:1;min-width:0}

/* ---------------- molecule detail page ---------------- */
.mol-view-card{padding:20px}
.mol-view{background:linear-gradient(180deg,#fff,#fbfaf7);border:1px solid var(--line);border-radius:10px;
  padding:24px;display:flex;align-items:center;justify-content:center;min-height:520px}
.mol-view-img{width:100%;height:100%;max-height:640px;object-fit:contain}
@media (max-width:960px){.mol-view{min-height:320px}}

/* ---------------- ratings + comments ---------------- */
.engage{background:var(--paper2);border:1px solid var(--line);border-radius:14px;padding:22px;margin:26px 0 32px}
.engage .note{font-size:.76rem;color:var(--ink-faint);background:#fff;border:1px dashed var(--line-strong);
  border-radius:8px;padding:8px 11px;margin-bottom:16px}
.stars{display:inline-flex;gap:3px;font-size:1.5rem;cursor:pointer}
.stars .star{color:var(--line-strong);transition:.1s;line-height:1}
.stars .star.on{color:var(--copper)}
.stars .star:hover{transform:scale(1.15)}
.rate-summary{font-size:.85rem;color:var(--ink-soft);margin-left:10px}
.cmt-form{display:flex;flex-direction:column;gap:9px;margin-top:16px}
.cmt-form textarea{font-family:inherit;font-size:.92rem;border:1px solid var(--line-strong);border-radius:9px;
  padding:11px;min-height:70px;resize:vertical}
.cmt-list{margin-top:18px;display:flex;flex-direction:column;gap:12px}
.cmt{background:#fff;border:1px solid var(--line);border-radius:10px;padding:12px 14px}
.cmt .who{font-size:.78rem;font-weight:600;color:var(--accent)}
.cmt .when{font-size:.72rem;color:var(--ink-faint)}
.cmt .txt{font-size:.92rem;margin-top:5px}

/* ---------------- map ---------------- */
.map-shell{background:#141816;border:1px solid #2C332E;border-radius:14px;overflow:hidden;position:relative}
#tmap{width:100%;height:620px;display:block;cursor:grab}
#tmap:active{cursor:grabbing}
.map-controls{position:absolute;top:14px;left:14px;display:flex;gap:8px;flex-wrap:wrap;z-index:5}
.map-controls .mc{background:rgba(20,24,22,.82);color:#DCE3DD;border:1px solid #333B34;border-radius:8px;
  padding:6px 11px;font-size:.8rem;cursor:pointer;backdrop-filter:blur(4px)}
.map-controls .mc.on{background:var(--accent);border-color:var(--accent);color:#fff}
.map-legend{position:absolute;bottom:14px;left:14px;font-family:var(--mono);font-size:.74rem;color:#B8BEB6;
  background:rgba(20,24,22,.82);border:1px solid #2C332E;border-radius:8px;padding:10px 12px;z-index:5}
.map-legend .grad{width:130px;height:9px;border-radius:3px;margin:6px 0 3px;
  background:linear-gradient(90deg,#0d0887,#6a00a8,#b83289,#f48849,#f0f921)}
.map-legend .ends{display:flex;justify-content:space-between;color:#8A9089;font-size:.68rem}
.map-tip{position:absolute;pointer-events:none;z-index:8;background:#fff;border:1px solid var(--line);
  border-radius:10px;padding:8px;box-shadow:0 12px 30px -12px rgba(0,0,0,.5);width:170px;display:none}
.map-tip img{width:100%;max-height:130px;object-fit:contain}
.map-tip .cap{font-family:var(--mono);font-size:.7rem;color:var(--ink-soft);text-align:center;margin-top:4px}

/* ---------------- footer ---------------- */
.foot{background:var(--paper2);padding:40px 0;border-top:1px solid var(--line)}
.foot .wrap{display:flex;justify-content:space-between;align-items:center;flex-wrap:wrap;gap:14px}
.foot .attr{font-size:.84rem;color:var(--ink-soft)}

.empty{text-align:center;color:var(--ink-faint);padding:60px 20px;font-size:.95rem}

@keyframes rise{from{opacity:0;transform:translateY(16px)}to{opacity:1;transform:none}}
@media (max-width:960px){
  .hero .wrap{grid-template-columns:1fr;gap:34px}
  .stats-band .wrap{grid-template-columns:repeat(2,1fr)}
  .stat+.stat{border-left:none;padding-left:0}
  .explore-grid{grid-template-columns:repeat(2,1fr)}
  .detail{grid-template-columns:1fr}
  .aside-card{position:static}
  .nav .links{display:none}
}
@media (prefers-reduced-motion:reduce){*{animation:none!important;transition:none!important}}

/* ---------------- back-to-top ---------------- */
#to-top{position:fixed;right:22px;bottom:22px;z-index:150;width:44px;height:44px;border-radius:50%;
  background:var(--accent);color:#fff;border:none;cursor:pointer;display:flex;align-items:center;justify-content:center;
  box-shadow:0 8px 22px -8px rgba(26,30,28,.5);opacity:0;transform:translateY(10px);pointer-events:none;
  transition:opacity .2s,transform .2s,background .15s}
#to-top.show{opacity:1;transform:translateY(0);pointer-events:auto}
#to-top:hover{background:#173a30}

/* ---------------- print / PDF export (route detail) ---------------- */
.print-only{display:none}
.cy-print{display:none}
@media print{
  @page{margin:14mm}
  /* reaction arrows are drawn with background/border colors, which browsers strip when printing —
     force exact color rendering so shafts + arrowheads survive in the PDF */
  *{-webkit-print-color-adjust:exact!important;print-color-adjust:exact!important}
  body{background:#fff;color:#000}
  .nav,.foot,.route-switch,.engage,.back,.no-print,.stars,.rate-summary{display:none!important}
  /* convergent/mixed figure: canvas prints blank, so show the rasterized PNG instead */
  .overview:has(.cy-print) .cy-tree{display:none!important}
  .cy-print{display:block!important;width:100%;height:auto;break-inside:avoid}
  .print-only{display:block}
  .print-head{font-family:var(--mono);font-size:.7rem;letter-spacing:.04em;color:var(--ink-soft);
    border-bottom:1px solid var(--line);padding-bottom:8px;margin-bottom:14px}
  .page{padding:0!important;min-height:0}
  .wrap{max-width:none;padding:0}
  .detail{display:block}
  .detail>div:last-child{margin-top:20px}
  .aside-card{position:static;margin:0 0 12px;break-inside:avoid}
  .overview,.step,.aside-card,.route-summary,.route-critic,.constraint-note{box-shadow:none!important;break-inside:avoid}
  .disclosure{display:block!important}          /* expand Reasoning + Mechanistic analysis in the PDF */
  .disclosure summary{display:none}
  .fig-modal{display:none!important}
  .cy-tree{border:none}
  .overview{border-color:var(--line)}
  a[href]{color:inherit;text-decoration:none}
  .aside-card,.step{page-break-inside:avoid}
}